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Mouse Anti-FAM19A3 Recombinant Antibody (CBYJT-1276) (CBMAB-T0291-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-1276
Antibody Isotype
IgG2b
Application
WB, ICFC, CyTOF

Basic Information

Immunogen
E. coli-derived recombinant human TAFA3/FAM19A3, Ala31-Arg133, Accession # Q7Z5A8
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 31-133

Target

Full Name
Family With Sequence Similarity 19 Member A3, C-C Motif Chemokine Like
Introduction
FAM19A3 is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to play a role as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for FAM19A3.
Entrez Gene ID
284467
UniProt ID
Q7Z5A8
Alternative Names
Family With Sequence Similarity 19 Member A3, C-C Motif Chemokine Like; Family With Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A3; Chemokine-Like Protein TAFA-3; TAFA3; Protein FAM19A3; TAFA-3
Research Area
Plays a role in the regulation of microglia polarization.
Biological Process
Negative regulation of microglial cell activation Source: UniProtKB
Neuroblast differentiation Source: GO_Central
Positive regulation of microglial cell activation Source: UniProtKB
Regulation of neuroblast proliferation Source: GO_Central
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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