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Mouse Anti-EEA1 Antibody (1F8) (CBMAB-0333-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
1F8
Antibody Isotype
IgG2b
Application
IP, WB, MA

Basic Information

Immunogen
Recombinant protein
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Supernatant
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Early Endosome Antigen 1
Introduction
EEA1 (early endosome antigen 1) is a protein that has protein homodimerization activity and 1-phosphatidylinositol binding. Diseases associated with EEA1 include subacute cutaneous lupus erythematosus and cat-scratch disease. Among its related pathways are immune system and endocytosis. An important paralog of this gene is FYCO1.
Entrez Gene ID
8411
UniProt ID
Q15075
Alternative Names
Early Endosome Antigen 1; Zinc Finger FYVE Domain-Containing Protein; Endosome-Associated Protein P162; Early Endosome Antigen 1, 162kD; ZFYVE2; Early Endosome-Associated Protein; MSTP105; MST105
Research Area
Binds phospholipid vesicles containing phosphatidylinositol 3-phosphate and participates in endosomal trafficking.
Biological Process
Early endosome to late endosome transport Source: UniProtKB
Endocytosis Source: UniProtKB
Synaptic vesicle to endosome fusion Source: UniProtKB
Vesicle fusion Source: UniProtKB
Viral RNA genome replication Source: ParkinsonsUK-UCL
Cellular Location
Early endosome membrane; Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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