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Mouse Anti-DYNC1I1 Recombinant Antibody (1091) (V2LY-0425-LY1134)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Zebrafish, Rat, Common fruit fly
Clone
1091
Antibody Isotype
IgG2b
Application
WB, IP, IF, FC, IHC

Basic Information

Immunogen
Purified cattle brain cytoplasmic dynein.
Host Species
Mouse
Specificity
Human, Mouse, Zebrafish, Rat, Common fruit fly
Antibody Isotype
IgG2b
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
BSA & PBS
Preservative
Sodium Azide
Concentration
1 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
dynein cytoplasmic 1 intermediate chain 1
Entrez Gene ID
613724
UniProt ID
Q29RQ3
Research Area
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.
Biological Process
Microtubule-based movement Source: GO_Central
Transport along microtubule Source: GO_Central
Vesicle transport along microtubule Source: UniProtKB
Cellular Location
Cytoplasm; Spindle pole; Kinetochore
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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