Mouse Anti-CRH Recombinant Antibody (CBXC-1691) (CBMAB-C3231-CQ)

Mouse

Human, Mouse, Rat

CBXC-1691

IgG2a, κ

ELISA, WB, IP

Amino acids 154-196 of human CRF.

Mouse

Human, Mouse, Rat

IgG2a, κ

Monoclonal Antibody

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
ELISA	1:100-1:1,000

Liquid

0.1% gelatin

0.09% sodium azide

0.1 mg/ml

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Corticotropin Releasing Hormone

Corticotropin-releasing hormone (CRH) (also known as corticotropin-releasing factor (CRF) or corticoliberin; corticotropin may also be spelled corticotrophin) is a peptide hormone involved in the stress response. It is a releasing hormone that belongs to corticotropin-releasing factor family.

CRH; CRF; CRH1; corticotropin releasing hormone

Hormone regulating the release of corticotropin from pituitary gland (By similarity).

Induces NLRP6 in intestinal epithelial cells, hence may influence gut microbiota profile (By similarity).

Associative learning Source: Ensembl
Cellular response to cocaine Source: Ensembl
Cellular response to dexamethasone stimulus Source: Ensembl
Chemical synaptic transmission Source: ProtInc
Diterpenoid metabolic process Source: Ensembl
Female pregnancy Source: UniProtKB
G protein-coupled receptor signaling pathway Source: Reactome
Hormone-mediated apoptotic signaling pathway Source: Ensembl
Hypothalamus development Source: Ensembl
Inflammatory response Source: UniProtKB
Ion homeostasis Source: Ensembl
Learning or memory Source: ProtInc
Long-term synaptic potentiation Source: Ensembl
Negative regulation of cell death Source: Ensembl
Negative regulation of circadian sleep/wake cycle, REM sleep Source: BHF-UCL
Negative regulation of epinephrine secretion Source: GO_Central
Negative regulation of gene expression Source: Ensembl
Negative regulation of glucagon secretion Source: GO_Central
Negative regulation of inflammatory response to antigenic stimulus Source: Reactome
Negative regulation of luteinizing hormone secretion Source: Ensembl
Negative regulation of norepinephrine secretion Source: Ensembl
Negative regulation of systemic arterial blood pressure Source: Ensembl
Parturition Source: ProtInc
Positive regulation of behavioral fear response Source: Ensembl
Positive regulation of calcium ion import Source: Ensembl
Positive regulation of cAMP-mediated signaling Source: Ensembl
Positive regulation of cell death Source: Ensembl
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of circadian sleep/wake cycle, wakefulness Source: BHF-UCL
Positive regulation of corticosterone secretion Source: Ensembl
Positive regulation of corticotropin secretion Source: UniProtKB
Positive regulation of cortisol secretion Source: BHF-UCL
Positive regulation of digestive system process Source: Ensembl
Positive regulation of gene expression Source: Ensembl
Positive regulation of insulin secretion involved in cellular response to glucose stimulus Source: Ensembl
Positive regulation of protein phosphorylation Source: Ensembl
Regulation of NMDA receptor activity Source: UniProtKB
Regulation of serotonin secretion Source: Ensembl
Response to corticosterone Source: Ensembl
Response to drug Source: Ensembl
Response to estrogen Source: Ensembl
Response to ethanol Source: Ensembl
Response to ether Source: Ensembl
Response to immobilization stress Source: Ensembl
Response to pain Source: Ensembl
Signal transduction Source: ProtInc
Steroid metabolic process Source: Ensembl
Synaptic transmission, dopaminergic Source: UniProtKB

Secreted