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Mouse Anti-CPNE6 Recombinant Antibody (CBWJC-3026) (V2LY-1206-LY974)

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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-3026
Antibody Isotype
IgG3, κ
Application
ELISA, WB

Basic Information

Immunogen
Full length recombinant CPNE6.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG3, κ
Clonality
Monoclonal Antibody

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
copine VI (neuronal)
Entrez Gene ID
UniProt ID
Function
Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellular processes. Binds phospholipid membranes in a calcium-dependent manner (By similarity).

Plays a role in dendrite formation by melanocytes (PubMed:23999003).
Biological Process
Cell differentiation Source: UniProtKB-KW
Cellular response to calcium ion Source: GO_Central
Chemical synaptic transmission Source: ProtInc
Glycerophospholipid biosynthetic process Source: Reactome
Lipid metabolic process Source: ProtInc
Nervous system development Source: ProtInc
Positive regulation of dendrite extension Source: UniProtKB
Vesicle-mediated transport Source: ProtInc
Cellular Location
Endosome; Cell membrane; Cytoplasm; Clathrin-coated vesicle; Perikaryon; Dendrite. Mainly cytoplasmic in absence of calcium. Associated predominantly with membranes in presence of calcium. Translocates to the cell membrane in a calcium-dependent manner. Colocalized with transferrin in intracellular clathrin-coated membrane vesicles in a calcium-dependent manner.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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