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Mouse Anti-COMMD3 Recombinant Antibody (2E2) (V2LY-1206-LY724)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2E2
Antibody Isotype
IgG2a, κ
Application
ELISA, IF

Basic Information

Immunogen
Full-length recombinant COMMD3.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
IF(ICC)10 μg/ml

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
COMM domain containing 3
Entrez Gene ID
23412
UniProt ID
Q9UBI1
Function
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237).

May down-regulate activation of NF-kappa-B (PubMed:15799966).

Modulates Na+ transport in epithelial cells by regulation of apical cell surface expression of amiloride-sensitive sodium channel (ENaC) subunits (PubMed:23637203).
Biological Process
Neutrophil degranulation Source: Reactome
Sodium ion transport Source: UniProtKB-KW
Cellular Location
Cytoplasm; Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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