Rat Anti-CNTN3 Recombinant Antibody (CBYY-C0314) (V2LY-1206-LY540)

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Summary

Host Animal

Rat

Specificity

Mouse

Clone

CBYY-C0314

Antibody Isotype

IgG2a

Application

FC, WB

Basic Information

Immunogen

Recombinant mouse Contactin‑3 Glu20-Thr1003.

Host Species

Rat

Specificity

Mouse

Antibody Isotype

IgG2a

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	2 µg/ml
FC	2.5 µg/10^6 cells

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, Trehalose

Preservative

None

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

Contactin 3

Entrez Gene ID

18488

UniProt ID

Q07409

Function

Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity (By similarity).

Biological Process

Cell adhesion Source: UniProtKB-KW
Nervous system development Source: Ensembl

Cellular Location

Cell membrane

More Infomation

References

Korotkov, A., Luinenburg, M. J., Romagnolo, A., Zimmer, T. S., van Scheppingen, J., Bongaarts, A., ... & Aronica, E. (2022). Down-regulation of the brain-specific cell-adhesion molecule contactin-3 in tuberous sclerosis complex during the early postnatal period. Journal of neurodevelopmental disorders, 14(1), 1-16.

Mamoor, S. (2021). CNTN3 is differentially expressed in lymph node metastasis in human breast cancer.

Zhou, J., Xie, Z., Cui, P., Su, Q., Zhang, Y., Luo, L., ... & Huang, J. (2020). SLC1A1, SLC16A9, and CNTN3 are potential biomarkers for the occurrence of colorectal cancer. BioMed Research International, 2020.

Zhu, Y. F., Guo, Y. B., Zhang, H. Y., Yang, P., Wei, D. F., Zhang, T. T., ... & Liu, L. (2019). Prognostic significance of contactin 3 expression and associated genes in glioblastoma multiforme. Oncology Letters, 18(2), 1863-1871.

Peng, X., Williams, J., Smallwood, P. M., & Nathans, J. (2019). Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis. Plos one, 14(7), e0219384.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Rabbit Anti-CNTN3 Recombinant Antibody (006)

Mouse Anti-CNTN3 Recombinant Antibody (CBYY-C3131)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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