Mouse Anti-CNIH4 Recombinant Antibody (A4145) (V2LY-1206-LY421)

Name: Mouse Anti-CNIH4 Recombinant Antibody (A4145)
SKU: V2LY-1206-LY421
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

A4145

Antibody Isotype

IgG2a, κ

Application

WB, ELISA, IP

Basic Information

Immunogen

Recombinant CNIH4 of human.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal Antibody

Application Notes

Application	Note
WB	1:100-1:1,000
IP	1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
ELISA	1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

0.1% gelatin

Preservative

<0.1% sodium azide

Concentration

0.1 mg/ml

Purity

>95% as determined by analysis by SDS-PAGE

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name

cornichon family AMPA receptor auxiliary protein 4

Entrez Gene ID

29097

UniProt ID

Q9P003

Function

Involved in G protein-coupled receptors (GPCRs) trafficking from the endoplasmic reticulum to the cell surface; it promotes the exit of GPCRs from the early secretory pathway, likely through interaction with the COPII machinery (PubMed:24405750).

Biological Process

Endoplasmic reticulum to Golgi vesicle-mediated transport Source: UniProtKB
Protein transport Source: UniProtKB-KW

Cellular Location

Endoplasmic reticulum; Membrane; Endoplasmic reticulum-Golgi intermediate compartment

More Infomation

References

Li, Y., Liu, H., & Han, Y. (2021). Potential Roles of Cornichon Family AMPA Receptor Auxiliary Protein 4 (CNIH4) in Head and Neck Squamous Cell Carcinoma.

Ramos-Vicente, D., & Bayés, À. (2020). AMPA receptor auxiliary subunits emerged during early vertebrate evolution by neo/subfunctionalization of unrelated proteins. Open biology, 10(10), 200234.

Jacobi, E., & von Engelhardt, J. (2018). AMPA receptor complex constituents: Control of receptor assembly, membrane trafficking and subcellular localization. Molecular and Cellular Neuroscience, 91, 67-75.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-CNIH4 Recombinant Antibody (4E10-1G4)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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