Mouse Anti-CMTM7 Recombinant Antibody (S1) (CBMAB-C3079-CQ)

See all CMTM7 antibodies

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human

Clone

Antibody Isotype

IgG

Application

ELISA

Basic Information

Immunogen

CMTM7 (AAH10116.1, 1aa-175aa) Full length recombinant protein with GST tag.

Specificity

Human

Antibody Isotype

IgG

Clonality

Monoclonal

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

CKLF Like MARVEL Transmembrane Domain Containing 7

Introduction

This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.

Entrez Gene ID

112616

UniProt ID

Q96FZ5

Alternative Names

CKLF Like MARVEL Transmembrane Domain Containing 7; Chemokine-Like Factor Superfamily Member 7; Chemokine-Like Factor Super Family 7; Chemokine-Like Factor Superfamily 7; CKLFSF7; CKLF-Like MARVEL Transmembrane Domain-Containing Protein 7; Chemokine-Like Factor Super Family Member 7 Variant 2; CKLF-Like MARVEL Transmembrane Domain Containing 7;

Biological Process

B-1a B cell differentiation Source: Ensembl
Chemotaxis Source: UniProtKB-KW

Cellular Location

Membrane

More Infomation

References

Lu, C., Zhao, Y., Wang, J., Shi, W., Dong, F., Xin, Y., ... & Liu, C. (2021). Breast cancer cell-derived extracellular vesicles transfer miR-182-5p and promote breast carcinogenesis via the CMTM7/EGFR/AKT axis. Molecular Medicine, 27(1), 1-17.

Liu, Z., Liu, Y., Li, T., Wang, P., Mo, X., Lv, P., ... & Han, W. (2020). CMTM7 plays key roles in TLR‐induced plasma cell differentiation and p38 activation in murine B‐1 B cells. European Journal of Immunology, 50(6), 809-821.

Huang, Z. M., Li, P. L., Yang, P., Hou, X. D., Yang, Y. L., Xu, X., & Xu, F. (2019). Overexpression of CMTM7 inhibits cell growth and migration in liver cancer. The Kaohsiung Journal of Medical Sciences, 35(6), 332-340.

Liu, Z., Liu, Y., Li, T., Wang, P., Mo, X., Lv, P., ... & Han, W. (2019). Cmtm7 knockout inhibits B-1a cell development at the transitional (TrB-1a) stage. International Immunology, 31(11), 715-728.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Related Products

Mouse Anti-CMTM7 Recombinant Antibody (2B1-G4)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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Documents

Datasheet
SDS
Request for COA

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Second antibody and isotype control

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