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Mouse Anti-CMPK1 Recombinant Antibody (CBWJC-2837) (CBMAB-C3959WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJC-2837
Antibody Isotype
IgG2b
Application
WB, IHC, IF

Basic Information

Immunogen
Full length human recombinant protein of human CMPK1(NP_057392) produced in HEK293T cell
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS (PH 7.3), 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
cytidine/uridine monophosphate kinase 1
Introduction
This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012]
Entrez Gene ID
51727
UniProt ID
P30085
Alternative Names
Cytidine/Uridine Monophosphate Kinase 1; UMP/CMP Kinase; Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic; Uridine Monophosphate/Cytidine Monophosphate Kinase; Nucleoside-Diphosphate Kinase; Deoxycytidylate Kinase; Cytidylate Kinase; UMP-CMP Kinase; DCMP Kinase; EC 2.7.4.14; CMPK; UMPK;
Function
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
Biological Process
de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
CDP biosynthetic process Source: GO_Central
Nucleobase-containing small molecule interconversion Source: Reactome
Nucleoside diphosphate phosphorylation Source: UniProtKB
Nucleoside triphosphate biosynthetic process Source: UniProtKB
Pyrimidine ribonucleotide biosynthetic process Source: ProtInc
UDP biosynthetic process Source: GO_Central
Cellular Location
Nucleus; Cytoplasm. Predominantly cytoplasmic, less than 15% nuclear.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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