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Mouse Anti-CMPK1 Recombinant Antibody (CBFYC-1972) (V2LY-1206-LY368)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Pig, Dog
Clone
CBFYC-1972
Antibody Isotype
IgG2b, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 92-196 mapping at the C-terminus of CMPK of human.
Host Species
Mouse
Specificity
Human, Mouse, Rat, Pig, Dog
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal Antibody
Application Notes
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
0.1% gelatin
Preservative
<0.1% sodium azide
Concentration
0.2 mg/ml
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
cytidine/uridine monophosphate kinase 1
Entrez Gene ID
Human51727
Mouse66588
UniProt ID
HumanP30085
MouseQ9DBP5
Function
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
Biological Process
de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
CDP biosynthetic process Source: GO_Central
Nucleobase-containing small molecule interconversion Source: Reactome
Nucleoside diphosphate phosphorylation Source: UniProtKB
Nucleoside triphosphate biosynthetic process Source: UniProtKB
Pyrimidine ribonucleotide biosynthetic process Source: ProtInc
UDP biosynthetic process Source: GO_Central
Cellular Location
Nucleus; Cytoplasm. Predominantly cytoplasmic, less than 15% nuclear.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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