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Mouse Anti-CDK20 Recombinant Antibody (885CT27.1.1) (CBMAB-C9006-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
885CT27.1.1
Antibody Isotype
IgG1
Application
WB, IP

Basic Information

Immunogen
His-tagged CCRK protein fragment of human.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Cyclin Dependent Kinase 20
Introduction
CDK20 (Cyclin Dependent Kinase 20) is a Protein Coding gene. Diseases associated with CDK20 include Attention Deficit-Hyperactivity Disorder and Seizure Disorder. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDK7.
Entrez Gene ID
23552
UniProt ID
Q8IZL9
Alternative Names
Cyclin Dependent Kinase 20; Cyclin-Kinase-Activating Kinase P42; Cyclin-Dependent Protein Kinase H; Cell Division Protein Kinase 20; Cell Cycle-Related Kinase; CDK-Activating Kinase P42; CAK-Kinase P42; EC 2.7.11.22;
Function
Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity).
Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Multicellular organism development Source: UniProtKB-KW
Protein phosphorylation Source: GO_Central
Cellular Location
Nucleus; Cytoplasm; Cilium
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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