Mouse Anti-CDK15 Recombinant Antibody (CBXC-2084) (CBMAB-C5622-CQ)

Name: Mouse Anti-CDK15 Recombinant Antibody (CBXC-2084)
SKU: CBMAB-C5622-CQ
Rating: 5 (1 reviews)

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Datasheet

Summary

Host Animal

Mouse

Specificity

Human, Mouse, Rat

Clone

CBXC-2084

Antibody Isotype

IgG2a

Application

Basic Information

Immunogen

Human recombinant protein fragment corresponding to amino acids 293-378 of human CDK15 produced in E.coli.

Host Species

Mouse

Specificity

Human, Mouse, Rat

Antibody Isotype

IgG2a

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS, pH 7.3, 1% BSA, 50% glycerol

Preservative

0.02% sodium azide

Concentration

1 mg/ml

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name

Cyclin Dependent Kinase 15

Introduction

CDK15 (Cyclin Dependent Kinase 15) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is CDK14.

Entrez Gene ID

65061

UniProt ID

Q96Q40

Alternative Names

Cyclin Dependent Kinase 15; Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 7 Protein; Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 7; Serine/Threonine-Protein Kinase PFTAIRE-2; Serine/Threonine-Protein Kinase ALS2CR7; Cell Division Protein Kinase 15; PFTAIRE Protein Kinase 2; EC 2.7.11.22;

Function

Serine/threonine-protein kinase that acts like an antiapoptotic protein that counters TRAIL/TNFSF10-induced apoptosis by inducing phosphorylation of BIRC5 at 'Thr-34'.

Biological Process

Protein phosphorylation Source: GO_Central
Regulation of transcription involved in G1/S transition of mitotic cell cycle Source: GO_Central

Cellular Location

Cytosol; Nucleus; Cytoplasm

More Infomation

References

Zhang, X., Wang, Q., Luo, Y., Song, M., Zhou, Z., Zeng, L., ... & Yang, C. (2021). Cyclin-dependent kinase 15 upregulation is correlated with poor prognosis for patients with breast cancer. Journal of International Medical Research, 49(6), 0300060521999552.

Li, S., Dai, X., Gong, K., Song, K., Tai, F., & Shi, J. (2019). PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15. Frontiers in oncology, 9, 1283.

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Protocols

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme-Linked Immunospot (ELISpot)
Proteogenomics
Other Protocols

Associated Products

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Datasheet
SDS
Request for COA

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

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