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Mouse Anti-CDIPT Recombinant Antibody (CBFYC-1576) (CBMAB-C1635-FY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBFYC-1576
Antibody Isotype
IgG1, κ
Application
WB, IP, IF, ELISA

Basic Information

Immunogen
Amino acids 57-79 within an internal region of PIS1 of human.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal Antibody
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
ELISA1:100-1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 1-213

Target

Full Name
CDP-Diacylglycerol--Inositol 3-Phosphatidyltransferase
Introduction
CDIPT (CDP-Diacylglycerol--Inositol 3-Phosphatidyltransferase) is a Protein Coding gene. Diseases associated with CDIPT include Epilepsy, Familial Temporal Lobe, 2 and Fibromuscular Dysplasia. Among its related pathways are Glycerophospholipid biosynthesis and Metabolism. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and manganese ion binding.
Entrez Gene ID
10423
UniProt ID
O14735
Alternative Names
CDP-Diacylglycerol--Inositol 3-Phosphatidyltransferase; Phosphatidylinositol Synthase; PtdIns Synthase; PI Synthase; PIS1; PIS; CDP-Diacylglycerol--Inositol 3-Phosphatidyltransferase (Phosphatidylinositol Synthase); EC 2.7.8.11
Function
Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns:inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme.
Biological Process
Phosphatidylinositol biosynthetic process Source: UniProtKB
Cellular Location
Cell membrane; Endoplasmic reticulum membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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