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Mouse Anti-CCNDBP1 Recombinant Antibody (CBLG1-2478) (CBMAB-G0014-LY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBLG1-2478
Antibody Isotype
IgG1, κ
Application
ELISA, IF, IP, WB

Basic Information

Immunogen
Amino acids 140-156 within an internal region of GCIP of human origin.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
ELISA1:100-1:1,000
IF(ICC)1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
cyclin D-type binding-protein 1
Introduction
CCNDBP1 (Cyclin D1 Binding Protein 1) is a Protein Coding gene. Diseases associated with CCNDBP1 include Optic Disk Drusen.
Entrez Gene ID
Human23582
Mouse17151
Rat362201
Dog607896
UniProt ID
HumanO95273
MouseQ3TVC7
RatQ5BK06
DogF6UX67
Alternative Names
Cyclin D1 Binding Protein 1; Grap2 And Cyclin-D-Interacting Protein; D-Type Cyclin-Interacting Protein 1; Cyclin D-Type Binding-Protein 1; Human Homolog Of Maid; DIP1;
Function
May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.
Biological Process
Cell cycle Source: UniProtKB-KW
Regulation of cell cycle Source: InterPro
Cellular Location
Nucleus; Cytoplasm
PTM
Phosphorylated.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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