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Mouse Anti-CCL15 Recombinant Antibody (CBFYC-0933) (CBMAB-C0989-FY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYC-0933
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
CCL15 (25 a.a. ~ 113 a.a) partial recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at-20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
AA 25-113

Target

Full Name
chemokine (C-C motif) ligand 15
Introduction
CCL15 (C-C Motif Chemokine Ligand 15) is a Protein Coding gene. Diseases associated with CCL15 include Gastrointestinal System Cancer and Spherocytosis, Type 5. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include receptor binding and chemokine activity. An important paralog of this gene is CCL15-CCL14.
Entrez Gene ID
6359
UniProt ID
Q16663
Alternative Names
C-C Motif Chemokine Ligand 15; Macrophage Inflammatory Protein 5; Chemokine CC-2; MIP-1 Delta; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 15; Chemokine (C-C Motif) Ligand 15; Small-Inducible Cytokine A15; Leukotactin 1; MRP-2B; SCYA15; HCC-2; LKN-1; MIP-5
Function
Chemotactic factor that attracts T-cells and monocytes, but not neutrophils, eosinophils, or B-cells. Acts mainly via CC chemokine receptor CCR1. Also binds to CCR3. CCL15(22-92), CCL15(25-92) and CCL15(29-92) are more potent chemoattractants than the small-inducible cytokine A15.
Biological Process
Cell-cell signaling Source: ProtInc
Cellular calcium ion homeostasis Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: GO_Central
Inflammatory response Source: GO_Central
lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Neutrophil chemotaxis Source: GO_Central
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Signal transduction Source: ProtInc
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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