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Mouse Anti-CCDC93 Recombinant Antibody (CBYY-C3206) (CBMAB-C4649-YY)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat, Dog, Monkey
Clone
CBYY-C3206
Antibody Isotype
IgG1
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 293-631 of human CCDC93 produced in E.coli.
Host Species
Mouse
Specificity
Human, Mouse, Rat, Dog, Monkey
Antibody Isotype
IgG1
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/ml
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Coiled-Coil Domain Containing 93
Entrez Gene ID
54520
UniProt ID
Q567U6
Alternative Names
AHUS5, ARMD9, ASPa, C3b, CPAMD1, HEL-S-62p, C3
Function
Component of the CCC complex, which is involved in the regulation of endosomal recycling of surface proteins, including integrins, signaling receptor and channels. The CCC complex associates with SNX17, retriever and WASH complexes to prevent lysosomal degradation and promote cell surface recycling of numerous cargos such as integrins ITGA5:ITGB1 (PubMed:28892079, PubMed:25355947).
Involved in copper-dependent ATP7A trafficking between the trans-Golgi network and vesicles in the cell periphery; the function is proposed to depend on its association within the CCC complex and cooperation with the WASH complex on early endosomes and is dependent on its interaction with WASHC2C (PubMed:25355947).
(Microbial infection) The CCC complex, in collaboration with the heterotrimeric retriever complex, mediates the exit of human papillomavirus to the cell surface.
Biological Process
Endocytic recycling Source: UniProtKB
Golgi to plasma membrane transport Source: UniProtKB
Protein transport Source: UniProtKB-KW
Cellular Location
Early endosome
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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