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Mouse Anti-BOD1L1 Recombinant Antibody (2A1) (CBMAB-A2822-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2A1
Antibody Isotype
IgG1, κ
Application
WB, E

Basic Information

Immunogen
FAM44A (AAH16987.1, 1 a.a. ~ 284 a.a) full-length recombinant protein with GST tag.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
Biorientation Of Chromosomes In Cell Division 1 Like 1
Entrez Gene ID
259282
UniProt ID
Q8NFC6
Alternative Names
FLJ33215; KIAA1327
Function
Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombinogenic activities of FBH1 and BLM (PubMed:26166705).
Does not regulate spindle orientation (PubMed:26166705).
Biological Process
Cellular response to DNA damage stimulus Source: UniProtKB
DNA repair Source: UniProtKB-KW
Negative regulation of phosphoprotein phosphatase activity Source: GO_Central
Replication fork processing Source: UniProtKB
Cellular Location
Chromosome. Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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