Search :
Sign in or Register  
Welcome Sign in or Don't have an account?Register

Mouse Anti-AZGP1 Recombinant Antibody (CBWJZ-007) (CBMAB-Z0012-WJ)


See all AZGP1 antibodies
Online Inquiry
Published Data
Mouse Anti-AZGP1 Recombinant Antibody (CBWJZ-007) in WB
Expression of PSA, ZAG and PIP is regulated by AR in breast cancer cell lines. Protein extracts of whole cell lysates were examined by western blot after 4-days cultured with vehicle control, DHT (10 nM), DHT (10 nM) plus Enza (20 μM) or Enza (20 μM). Each band was quantifed by densitometry and the expression levels of ZAG relative to GAPDH normalized to vehicle control are shown for representative cell lines. ...View More
Hanamura, T., Christenson, J. L., O'Neill, K. I., Rosas, E., Spoelstra, N. S., Williams, M. M., & Richer, J. K. (2021). Secreted indicators of androgen receptor activity in breast cancer pre-clinical models. Breast Cancer Research, 23(1), 1-15.
Mouse Anti-AZGP1 Recombinant Antibody (CBWJZ-007) in WB
ZAG gene and protein expression in differentiated human primary adipocytes. Representative western blot shows ZAG protein in siRNA transfected adipocytes when compared to control - scramble transfected cells. ...View More
Balaž, M., Ukropcova, B., Kurdiova, T., Vlcek, M., Surova, M., Krumpolec, P., ... & Ukropec, J. (2015). Improved adipose tissue metabolism after 5-year growth hormone replacement therapy in growth hormone deficient adults: the role of zinc-α2-glycoprotein. Adipocyte, 4(2), 113-122.
Mouse Anti-AZGP1 Recombinant Antibody (CBWJZ-007) in WB
Zinc-a2-glycoprotein is regulated by growth hormone in GH deficient adults. Adipose tissue mRNA and protein levels of ZAG (A) in adults with growth hormone deficiency (GHD; cohort 1). (B) Effect of GH replacement therapy on adipose tissue mRNA, protein and circulating levels of ZAG. (C) Normalization of ZAG mRNA and protein in adipose tissue of GH treated GHD patients to levels found in healthy age-, gender- and BMI-matched controls (cohort 2). C, healthy control individuals; GHD, patients with growth hormone deficiency; GHt, GHD patients treated 5 years with growth hormone; ZAG, zinc-a2-glycoprotein; Student's T test was used to evaluate differences between the groups and *P < 0.05, **P < 0.01, ***P < 0.001. ...View More
Balaz, M., Ukropcova, B., Kurdiova, T., Gajdosechova, L., Vlcek, M., Janakova, Z., ... & Ukropec, J. (2015). Adipokine zinc-α2-glycoprotein regulated by growth hormone and linked to insulin sensitivity. Obesity, 23(2), 322-328.
Mouse Anti-AZGP1 Recombinant Antibody (CBWJZ-007) in IHC
Extracellular distribution of ZAG around numerous blood capillaries in the brain of a patient with Krabbe's disease. Magn. ×100. Inserts: A) Capillaries of cerebellar white matter. Magn. ×200; B) capillaries in cerebellar grey matter. Magn. ×200. ...View More
Maślińska, D., Laure-Kamionowska, M., & Maśliński, S. (2013). Crosstalk in human brain between globoid cell leucodystrophy and zinc-alpha-2-glycoprotein (ZAG), a biomarker of lipid catabolism. Folia Neuropathologica, 51(4), 312-318.

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBWJZ-007
Antibody Isotype
IgG1, κ
Application
WB, IP, IF, IHC-P

Basic Information

Immunogen
Full length ZAG of human origin.
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:100-1:1,000
IP1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)
IF(ICC)1:50-1:500
IHC-P1:50-1:500

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, 0.1% gelatin
Preservative
< 0.1% sodium azide
Concentration
0.2 mg/ml

Target

Full Name
Alpha-2-Glycoprotein 1, Zinc-Binding
Introduction
AZGP1 (Alpha-2-Glycoprotein 1, Zinc-Binding) is a Protein Coding gene. Diseases associated with AZGP1 include Hidrocystoma and Clear Cell Hidradenoma. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Miscellaneous transport and binding events. Gene Ontology (GO) annotations related to this gene include antigen binding and peptide antigen binding. An important paralog of this gene is HFE.
Entrez Gene ID
563
UniProt ID
P25311
Alternative Names
ZAG; ZA2G
Function
Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids.
Biological Process
Antigen processing and presentation of endogenous peptide antigen via MHC class Ib Source: GO_Central
Cell adhesion Source: UniProtKB
Detection of chemical stimulus involved in sensory perception of bitter taste Source: UniProtKB
Negative regulation of cell population proliferation Source: UniProtKB
Retina homeostasis Source: UniProtKB
Transmembrane transport Source: Reactome
Cellular Location
Secreted
PTM
N-glycosylated. N-glycan at Asn-128: Hex5HexNAc4.
More Infomation
Ask a question We look forward to hearing from you.
0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Loading...
Have you used Mouse Anti-AZGP1 Recombinant Antibody (CBWJZ-007)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon $30 eGift Card
Submit a review
Loading...
For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Learn more

Documents

Request bulk or custom quote Online Inquiry
Second antibody and isotype control

Contact us

  • Tel: (USA)
  • (UK)
  • Fax:
  • Email:

Submit A Review

Online Inquiry