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Rabbit Anti-AFAP1L2 Recombinant Antibody (V2-180052) (CBMAB-A1459-YC)


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Summary

Host Animal
Rabbit
Specificity
Human, Monkey
Clone
V2-180052
Antibody Isotype
IgG
Application
WB, IP

Basic Information

Immunogen
Synthetic peptide corresponding to residues surrounding Gly638 of human AFAP1L2/XB130 protein.
Host Species
Rabbit
Specificity
Human, Monkey
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:1,000
IP1:50

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
HEPES, pH 7.5, 100 µg/ml BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Actin Filament Associated Protein 1 Like 2
Introduction
AFAP1L2 may play a role in a signaling cascade by enhancing the kinase activity of SRC aand contributes to SRC-regulated transcription activation.
Entrez Gene ID
Human84632
Monkey698518
UniProt ID
HumanQ8N4X5
MonkeyA0A2K6UTU6
Alternative Names
Actin Filament Associated Protein 1 Like 2; KIAA1914; AFAP1-Like Protein 2; XB130; Actin Filament Associated Protein 1-Like 2; Actin Filament-Associated Protein 1-Like 2; CTB-1144G6.4; CTB-1144G6.6;
Function
May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.
Biological Process
Inflammatory response
Positive regulation of epidermal growth factor receptor signaling pathway
Positive regulation of interleukin-8 production
Positive regulation of transcription, DNA-templated
Regulation of interleukin-6 production
Regulation of mitotic cell cycle
Cellular Location
Cytoplasm
PTM
Tyrosine phosphorylated (by SRC).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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