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Mouse Anti-ADH5 Recombinant Antibody (V2-179904) (CBMAB-A1288-YC)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
V2-179904
Antibody Isotype
IgG2b
Application
WB

Basic Information

Immunogen
Human recombinant protein fragment corresponding to amino acids 1-266 of human ADH5 (NP_000662) produced in E. coli
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Buffer
PBS, pH7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
1 mg/ml
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Alcohol Dehydrogenase 5 (Class III), Chi Polypeptide
Introduction
ADH5 is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homod
Entrez Gene ID
128
UniProt ID
P11766
Alternative Names
Alcohol Dehydrogenase 5 (Class III), Chi Polypeptide; Glutathione-Dependent Formaldehyde Dehydrogenase; S-(Hydroxymethyl)Glutathione Dehydrogenase; Alcohol Dehydrogenase Class Chi Chain; Alcohol Dehydrogenase Class-III; S-Nitrosoglutathione Reductase; For
Function
Catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Class-III ADH is remarkably ineffective in oxidizing ethanol.
Biological Process
Ethanol oxidation
Fatty acid omega-oxidation
Formaldehyde catabolic process
Peptidyl-cysteine S-nitrosylation
Positive regulation of blood pressure
Respiratory system process
Response to lipopolysaccharide
Response to nitrosative stress
Response to redox state
Retinoid metabolic process
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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