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Rabbit Anti-ACHE Recombinant Antibody (V2-6060) (CBMAB-0005CQ)


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Published Data
Rabbit Anti-ACHE Recombinant Antibody (BA0179) (CBMAB-0005CQ) in WB
The Western blot results of AChE expression in different rat hippocampus. ...View More
Hour, F. Q., Moghadam, A. J., Shakeri-Zadeh, A., Bakhtiyari, M., Shabani, R., & Mehdizadeh, M. (2020). Magnetic targeted delivery of the SPIONs-labeled mesenchymal stem cells derived from human Wharton's jelly in Alzheimer's rat models. Journal of Controlled Release, 321, 430-441.
Rabbit Anti-ACHE Recombinant Antibody (BA0179) (CBMAB-0005CQ) in IHC
Immunohistochemistry of gastrocneminus at different recovery times after exercise-induced fatigue. ...View More
Wen, G., Hui, W., Dan, C., Xiao-Qiong, W., Jian-Bin, T., Chang-Qi, L., ... & Xue-Gang, L. (2009). The effects of exercise-induced fatigue on acetylcholinesterase expression and activity at rat neuromuscular junctions. Acta histochemica et cytochemica, 42(5), 137-142.

Summary

Host Animal
Rabbit
Specificity
Mouse, Rat
Clone
V2-6060
Antibody Isotype
IgG
Application
IHC-Fr, IHC-P, WB

Basic Information

Immunogen
Mouse Acetylcholinesterase aa 50-150
Specificity
Mouse, Rat
Antibody Isotype
IgG
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:1,000
IHC-P1:50
IHC-F1:1,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH7.2, 0.05% BSA, 40% Glycerol
Preservative
0.1% sodium azide
Concentration
Batch dependent
Purity
>95% as determined by analysis by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Acetylcholinesterase (Cartwright Blood Group)
Introduction
Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. Synapses usually contain asymmetric molecules of cholinesterase, with a collagen-like part disulfide-bonded to the catalytic part. A different, globular type of cholinesterase occurs on the outer surfaces of cell membranes, including those of erythrocytes. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally.
Entrez Gene ID
Mouse11423
Rat83817
UniProt ID
MouseP21836
RatP37136
Alternative Names
ACHE; Acetylcholinesterase (Yt blood group)
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For research use only. Not intended for any clinical use.

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We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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