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AKR1C2 Matched Antibody Pair (053) (APMAB-053LY)

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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-AKR1C2 polyclonal antibody, 100 ug
Detection Antibody
Anti-AKR1C2 Mouse polyclonal antibody, 40 ul
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Alternative Names
Aldo-Keto Reductase Family 1 Member C2; Dihydrodiol Dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase, Type III; Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase; Testicular 17,20-Desmolase Deficiency; Chlordecone Reductase Homolog HAKRD; 3-Alpha-HSD3; DD/BABP; DDH2; DD-2; DD2; Aldo-Keto Reductase Family 1, Member C2 (Dihydrodiol Dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase, Type III); Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein; Type III 3-Alpha-Hydroxysteroid Dehydrogenase; Type II Dihydrodiol Dehydrogenase; Pseudo-Chlordecone Reductase;
Entrez Gene ID
UniProt ID
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For research use only. Not intended for any clinical use.

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