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TPP1 Matched Antibody Pair (1263) (APMAB-1263LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-TPP1 monoclonal antibody, 100 ug
Detection Antibody
Anti-TPP1 Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
Alternative Names
Tripeptidyl Peptidase 1; Cell Growth-Inhibiting Gene 1 Protein; Tripeptidyl Aminopeptidase; Tripeptidyl Peptidase I; EC 3.4.14.9; TPP-1; CLN2; LPIC; Ceroid-Lipofuscinosis, Neuronal 2, Late Infantile (Jansky-Bielschowsky Disease); Spinocerebellar Ataxia, Autosomal Recessive 7;
Entrez Gene ID
1200
UniProt ID
O14773
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For research use only. Not intended for any clinical use.

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