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TNFRSF17

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
Full Name
TNFRSF17 Gene(Protein Coding) TNF Receptor Superfamily Member 17
Function
Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.
Biological Process
Biological Process adaptive immune response Source:UniProtKB-KW
Biological Process lymphocyte homeostasis Source:Ensembl
Biological Process signal transduction Source:ProtInc1 Publication
Biological Process tumor necrosis factor-mediated signaling pathway Source:InterPro
Cellular Location
Cell membrane
Endomembrane system
Involvement in disease
A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.
Topology
Extracellular: 1-54
Helical: 55-77
Cytoplasmic: 78-184

Anti-TNFRSF17 antibodies

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Rabbit Anti-TNFRSF17 Recombinant Antibody (E6D7B) (CBMAB-CP2803-LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: E6D7B
Application*: WB, IP, P, F

Mouse Anti-TNFRSF17 Recombinant Antibody (8H2) (CBMAB-A9300-LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG2a, λ
Specificity: Human
Clone: 8H2
Application*: WB, E

Mouse Anti-TNFRSF17 Recombinant Antibody (8B4) (CBMAB-A9299-LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 8B4
Application*: WB, E

Mouse Anti-TNFRSF17 Recombinant Antibody (3D1) (CBMAB-A9297-LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3D1
Application*: WB, E

Mouse Anti-TNFRSF17 Recombinant Antibody (1A4) (CBMAB-A9295-LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1A4
Application*: WB, E

Mouse Anti-TNFRSF17 Recombinant Antibody (BCMA/2366) (CBMAB-T6012-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: BCMA/2366
Application*: PA, P

Mouse Anti-TNFRSF17 Recombinant Antibody (8E11) (CBMAB-T6011-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 8E11
Application*: WB, E

Rat Anti-Tnfrsf17 Recombinant Antibody (6D163) (CBMAB-T6010-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 6D163
Application*: F, IP, WB

Mouse Anti-TNFRSF17 Recombinant Antibody (3H6) (CBMAB-T6009-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3H6
Application*: E, WB

Rat Anti-TNFRSF17 Recombinant Antibody (3D44) (CBMAB-T6008-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: 3D44
Application*: WB, N

Mouse Anti-TNFRSF17 Recombinant Antibody (1F10) (CBMAB-T6007-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1F10
Application*: E, WB

Mouse Anti-TNFRSF17 Recombinant Antibody (1D12G9) (CBMAB-T6006-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1D12G9
Application*: WB, E, F

Rat Anti-Tnfrsf17 Recombinant Antibody (Vicky-2) (CBMAB-T6005-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: Vicky-2
Application*: IP, F, WB, FN, B

Rat Anti-TNFRSF17 Recombinant Antibody (Vicky-1) (CBMAB-T6004-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: Vicky-1
Application*: WB, E, F, IC, IF, IH, B

Mouse Anti-TNFRSF17 Recombinant Antibody (CBYJT-6002) (CBMAB-T6002-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-6002
Application*: WB, IP, IF, E

Rabbit Anti-TNFRSF17 Recombinant Antibody (CBYJT-6001) (CBMAB-T6001-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-6001
Application*: WB, IP, P, F

Human Anti-TNFRSF17 Recombinant Antibody (CBXC-0803) (CBMAB-C1917-CQ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXC-0803
Application*: F

Rat Anti-Tnfrsf17 Recombinant Antibody (CBYJT-3758) (CBMAB-T3141-YJ)

Datasheet Datasheet SDS SDS
Target: Tnfrsf17
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJT-3758
Application*: WB, N

Rat Anti-Tnfrsf17 Recombinant Antibody (CBYJT-3757) (CBMAB-T3140-YJ)

Datasheet Datasheet SDS SDS
Target: Tnfrsf17
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYJT-3757
Application*: N, WB

Rat Anti-TNFRSF17 Recombinant Antibody (CBYJT-3756) (CBMAB-T3139-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3756
Application*: IC, F

Mouse Anti-TNFRSF17 Recombinant Antibody (CBYJT-3755) (CBMAB-T3138-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-3755
Application*: E, F

Mouse Anti-TNFRSF17 Recombinant Antibody (CBYJT-3754) (CBMAB-T3137-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3754
Application*: E, WB

Mouse Anti-TNFRSF17 Recombinant Antibody (CBYJT-3753) (CBMAB-T3136-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3753
Application*: E, WB

Mouse Anti-TNFRSF17 Recombinant Antibody (CBYJT-3752) (CBMAB-T3135-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYJT-3752
Application*: WB, B

Mouse Anti-TNFRSF17 Recombinant Antibody (CBYJT-3751) (CBMAB-T3134-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3751
Application*: E, WB

Rat Anti-TNFRSF17 Recombinant Antibody (CBYJT-3750) (CBMAB-T3133-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rat
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJT-3750
Application*: F, IC

Mouse Anti-TNFRSF17 Recombinant Antibody (CBYJT-3749) (CBMAB-T3132-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-3749
Application*: E, WB

Mouse Anti-TNFRSF17 Recombinant Antibody (CBYJT-3748) (CBMAB-T3131-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJT-3748
Application*: E, WB

Rat Anti-TNFRSF17 Recombinant Antibody (CBYJT-3747) (CBMAB-T3130-YJ)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYJT-3747
Application*: N, WB

Mouse Anti-TNFRSF17 Recombinant Antibody (CBFYC-3171) (CBMAB-C3248-FY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYC-3171
Application*: F

TNFRSF17 Matched Antibody Pair (1227) (APMAB-1227LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Specificity: Human

TNFRSF17 Matched Antibody Pair (1226) (APMAB-1226LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Specificity: Human

TNFRSF17 Matched Antibody Pair (1225) (APMAB-1225LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Specificity: Human

TNFRSF17 Matched Antibody Pair (1224) (APMAB-1224LY)

Datasheet Datasheet SDS SDS
Target: TNFRSF17
Specificity: Human
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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