SERPINA3

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jul 2008]
Full Name
Serpin Family A Member 3
Function
Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
Biological Process
Biological Process acute-phase responseIEA:UniProtKB-KW
Biological Process inflammatory response1 PublicationNAS:UniProtKB
Biological Process maintenance of gastrointestinal epithelium1 PublicationNAS:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentIBA:GO_Central
Biological Process regulation of lipid metabolic process1 PublicationNAS:UniProtKB
Cellular Location
Secreted
PTM
N- and O-glycosylated.
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Anti-SERPINA3 antibodies

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Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3F5
Application*: SE, E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CF003
Application*: ELISA, WB, IHC
Target: SERPINA3
Host: Mouse
Specificity: Human
Clone: CBXS-3098
Application*: E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXS-2765
Application*: E, IH, IP, WB
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXS-2708
Application*: E, IH
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-1704
Application*: WB
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1081
Application*: EC
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-1062
Application*: E, ED
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-3845
Application*: E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-3844
Application*: E
Target: SERPINA3
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXS-3660
Application*: F, IC, IF
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5977
Application*: WB
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5849
Application*: P, WB
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5822
Application*: E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-5610
Application*: E, WB, IH
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AACT/1452
Application*: WB, F, IF, P, MC
Target: SERPINA3
Host: Mouse
Specificity: Human
Clone: CBXS-5769
Application*: WB, F, E, IH, P, MC
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 10-143.1
Application*: E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 10-118.2
Application*: E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 5G3C11
Application*: E, F, IH, P, WB
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT2665
Application*: WB, IH, F
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0426
Application*: WB, E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0425
Application*: WB, E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0424
Application*: WB, E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0423
Application*: WB, E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0422
Application*: WB, E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0421
Application*: WB, E
Target: SERPINA3
Host: Mouse
Specificity: Human
Clone: IHC501
Application*: IH
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-A1042
Application*: E
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: ACT14C7
Application*: C, P
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AACT/1451
Application*: WB, P, IF, IC, F
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 71A1
Application*: IH, WB
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1E6
Application*: E, P, IP, WB
Target: SERPINA3
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C10
Application*: E, P
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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