SCGB1A1

This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010]

Secretoglobin Family 1A Member 1

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

Biological Process embryo implantationManual Assertion Based On ExperimentTAS:ProtInc
Biological Process female pregnancy1 PublicationNAS:ProtInc
Biological Process negative regulation of interferon-gamma productionIEA:Ensembl
Biological Process negative regulation of interleukin-13 productionIEA:Ensembl
Biological Process negative regulation of interleukin-4 productionIEA:Ensembl
Biological Process negative regulation of interleukin-5 productionIEA:Ensembl
Biological Process negative regulation of T cell proliferationIEA:Ensembl
Biological Process negative regulation of transcription by RNA polymerase IIIEA:Ensembl
Biological Process regulation of inflammatory responseIEA:Ensembl
Biological Process regulation of mRNA stabilityIEA:Ensembl
Biological Process response to cytokineIEA:Ensembl
Biological Process response to fibroblast growth factorIEA:Ensembl
Biological Process response to glucocorticoidIEA:Ensembl
Biological Process response to lipopolysaccharideIEA:Ensembl
Biological Process response to ozoneIEA:Ensembl
Biological Process response to silicon dioxideIEA:Ensembl
Biological Process response to xenobiotic stimulusIEA:Ensembl
Biological Process signal transduction1 PublicationNAS:ProtInc
Biological Process T cell proliferationIEA:Ensembl

Secreted