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POU2F1

The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.
Full Name
POU class 2 homeobox 1
Function
Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR.
(Microbial infection) In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.
Biological Process
Negative regulation of transcription, DNA-templatedManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:NTNU_SB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Nucleus
PTM
Phosphorylated by PRKDC.

Anti-POU2F1 antibodies

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Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB230A
Application*: ELISA, WB
Target: POU2F1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: D7B6
Application*: WB, IP, CI, CI-seq
Target: POU2F1
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1E12
Application*: WB, E
Target: POU2F1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: YL15
Application*: EMSA, IP, WB
Target: POU2F1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: POU5I097
Application*: WB, F, DB, ICC, IF
Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CB332
Application*: WB, IHC
Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNC-685
Application*: WB, P
Target: POU2F1
Host: Mouse
Specificity: Human
Clone: 27-7G1
Application*: WB
Target: POU2F1
Host: Mouse
Specificity: Mouse, Human, Frog
Clone: CBXO-0463
Application*: WB, IP, IF, P
Target: POU2F1
Host: Mouse
Specificity: Human
Clone: CBXO-0336
Application*: WB, IP, IF, E
Target: POU2F1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBXO-0424
Application*: WB, IP, CI
Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 2C5
Application*: WB, IP, IF, P, F, E
Target: POU2F1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: 5G3
Application*: WB
More Infomation
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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