PKD1L2

This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

polycystic kidney disease 1-like 2

May function as an ion-channel regulator. May function as a G-protein-coupled receptor.

Detection of mechanical stimulusManual Assertion Based On ExperimentIBA:GO_Central

Membrane

Extracellular: 18-1344
Helical: 1345-1365
Cytoplasmic: 1366-1552
Helical: 1553-1573
Extracellular: 1574-1594
Helical: 1595-1615
Cytoplasmic: 1616-1818
Helical: 1819-1839
Extracellular: 1840-1865
Helical: 1866-1886
Cytoplasmic: 1887-1943
Helical: 1944-1964
Extracellular: 1965-2143
Helical: 2144-2166
Cytoplasmic: 2167-2182
Helical: 2183-2203
Extracellular: 2204-2218
Helical: 2219-2239
Cytoplasmic: 2240-2270
Helical: 2271-2291
Extracellular: 2292-2312
Helical: 2313-2333
Cytoplasmic: 2334-2377
Helical: 2378-2398
Extracellular: 2399-2459