MBIP

MBIP (MAP3K12 Binding Inhibitory Protein 1) is a Protein Coding gene. Among its related pathways are Chromatin organization. Gene Ontology (GO) annotations related to this gene include identical protein binding and protein kinase inhibitor activity.

MAP3K12 Binding Inhibitory Protein 1

Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.

Histone H3 acetylation Source: BHF-UCL
Histone H3-K14 acetylation Source: ComplexPortal
Positive regulation of gene expression Source: GO_Central
Positive regulation of JNK cascade Source: GO_Central
Regulation of cell cycle Source: ComplexPortal
Regulation of cell division Source: ComplexPortal
Regulation of embryonic development Source: ComplexPortal
Regulation of histone deacetylation Source: ComplexPortal
Regulation of transcription, DNA-templated Source: ComplexPortal
Regulation of transcription by RNA polymerase II Source: ComplexPortal
Regulation of tubulin deacetylation Source: ComplexPortal

Nucleus
Cytoplasm and Cytosol
Note: Shows a cytoplasmic localization when coexpressed with MAP3K12.