CXCR6

CXCR6 (C-X-C Motif Chemokine Receptor 6) is a Protein Coding gene. Diseases associated with CXCR6 include Sarcoidosis 1 and Xanthogranulomatous Cholecystitis. Among its related pathways are Akt Signaling and Peptide ligand-binding receptors. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-X-C chemokine receptor activity. An important paralog of this gene is CCR7.

C-X-C Motif Chemokine Receptor 6

Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.

Calcium-mediated signaling Source: GO_Central
Cell chemotaxis Source: GO_Central
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Inflammatory response Source: InterPro
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Viral genome replication Source: ProtInc

Cell membrane

Extracellular: 1-32
Helical: 33-59
Cytoplasmic: 60-68
Helical: 69-89
Extracellular: 90-103
Helical: 104-125
Cytoplasmic: 126-143
Helical: 144-164
Extracellular: 165-187
Helical: 188-215
Cytoplasmic: 216-231
Helical: 232-259
Extracellular: 260-275
Helical: 276-293
Cytoplasmic: 294-342