CRABP2

CRABP2 (Cellular Retinoic Acid Binding Protein 2) is a Protein Coding gene. Diseases associated with CRABP2 include Embryonal Carcinoma and Basal Cell Carcinoma. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and PEDF Induced Signaling. Gene Ontology (GO) annotations related to this gene include transporter activity and retinol binding. An important paralog of this gene is CRABP1.

Full Name

Cellular Retinoic Acid Binding Protein 2

Function

Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.

Biological Process

Embryonic forelimb morphogenesis Source: Ensembl
Epidermis development Source: ProtInc
Positive regulation of collateral sprouting Source: Ensembl
Regulation of transcription, DNA-templated Source: ProtInc
Retinoic acid metabolic process Source: Ensembl
Signal transduction Source: ProtInc

Cellular Location

Cytoplasm; Nucleus; Endoplasmic reticulum. Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.

PTM

Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation.

Anti-CRABP2 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-CRABP2 Recombinant Antibody (CBFYC-2181) (V2LY-1206-LY1066)

Datasheet

SDS

Target: CRABP2

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Rat, Pig

Clone: CBFYC-2181

Application*: WB, IF, IH

Mouse Anti-CRABP2 Recombinant Antibody (CBFYC-0423) (V2LY-1206-LY1065)

Datasheet

SDS

Target: CRABP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat, Pig

Clone: CBFYC-0423

Application*: WB, IF, IH

Mouse Anti-CRABP2 Recombinant Antibody (CBFYC-0056) (V2LY-1206-LY1064)

Datasheet

SDS

Target: CRABP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-0056

Application*: F, IF

Mouse Anti-CRABP2 Recombinant Antibody (4F2) (V2LY-1206-LY1063)

Datasheet

SDS

Target: CRABP2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4F2

Application*: E, WB, IF

Rabbit Anti-CRABP2 Recombinant Antibody (016) (V2LY-1206-LY1062)

Datasheet

SDS

Target: CRABP2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 016

Application*: E

Mouse Anti-CRABP2 Recombinant Antibody (01) (V2LY-1206-LY1061)

Datasheet

SDS

Target: CRABP2

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 01

Application*: WB, E

Rabbit Anti-CRABP2 Recombinant Antibody (4) (V2LY-1206-LY1060)

Datasheet

SDS

Target: CRABP2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 4

Application*: WB

Mouse Anti-CRABP2 Recombinant Antibody (2E11) (V2LY-1206-LY1059)

Datasheet

SDS

Target: CRABP2

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Mouse

Clone: 2E11

Application*: WB, F, IF, E

Mouse Anti-CRABP2 Recombinant Antibody (05) (V2LY-1206-LY1058)

Datasheet

SDS

Target: CRABP2

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 05

Application*: P

Rabbit Anti-CRABP2 Recombinant Antibody (004) (V2LY-1206-LY1057)

Datasheet

SDS

Target: CRABP2

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 004

Application*: WB, F, IF, IP

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)