CD58

CD58 (CD58 Molecule) is a Protein Coding gene. Diseases associated with CD58 include Whipple Disease and Oral Lichen Planus. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Innate Immune System. Gene Ontology (GO) annotations related to this gene include receptor binding.

Full Name

CD58 Molecule

Function

Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells, antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Biological Process

Cell-cell adhesion Source: UniProtKB
Cellular response to interferon-gamma Source: UniProtKB
Cellular response to tumor necrosis factor Source: UniProtKB
Heterotypic cell-cell adhesion Source: UniProtKB
Leukocyte migration Source: Reactome
Neutrophil degranulation Source: Reactome
Positive regulation of interleukin-8 production Source: UniProtKB

Cellular Location

Cell membrane

Topology

Extracellular: 29-215
Helical: 216-238
Cytoplasmic: 239-250

Anti-CD58 antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

CD58 Matched Antibody Pair (231) (APMAB-231LY)

Datasheet

SDS

Target: CD58

Specificity: Human

Mouse Anti-CD58 Recombinant Antibody (BRIC-5) (CBMAB-C1860-CN)

Datasheet

SDS

Target: CD58

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: BRIC-5

Application*: F, WB

Rabbit Anti-CD58 Recombinant Antibody (CBYY-C0267) (CBMAB-C0782-YY)

Datasheet

SDS

Target: CD58

Host: Rabbit

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYY-C0267

Application*: WB, IP

Mouse Anti-CD58 Recombinant Antibody (CBFYC-1369) (CBMAB-C1427-FY)

Datasheet

SDS

Target: CD58

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-1369

Application*: E

Mouse Anti-CD58 Recombinant Antibody (CBFYC-0472) (CBMAB-C0518-FY)

Datasheet

SDS

Target: CD58

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYC-0472

Application*: E, WB

Mouse Anti-CD58 Recombinant Antibody (CBFYC-0381) (CBMAB-C0421-FY)

Datasheet

SDS

Target: CD58

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-0381

Application*: F, IF

Mouse Anti-CD58 Recombinant Antibody (CBFYC-0168) (CBMAB-C0191-FY)

Datasheet

SDS

Target: CD58

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYC-0168

Application*: F, IP, WB

Mouse Anti-CD58 Recombinant Antibody (CBFYC-0167) (CBMAB-C0190-FY)

Datasheet

SDS

Target: CD58

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYC-0167

Application*: F, IP, WB

Mouse Anti-CD58 Recombinant Antibody (2D11-B10) (CBMAB-C4867-LY)

Datasheet

SDS

Target: CD58

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 2D11-B10

Application*: E, IF, P, WB

Rabbit Anti-CD58 Recombinant Antibody (CBYJL-1015) (CBMAB-L0425-YJ)

Datasheet

SDS

Target: CD58

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBYJL-1015

Application*: P

Rabbit Anti-CD58 Recombinant Antibody (083) (CBMAB-L0424-YJ)

Datasheet

SDS

Target: CD58

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 083

Application*: F, E

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)