CD1B

CD1B (CD1b Molecule) is a Protein Coding gene. Diseases associated with CD1B include Mycobacterium Malmoense and Mycobacterium Tuberculosis 1. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. Gene Ontology (GO) annotations related to this gene include beta-2-microglobulin binding and endogenous lipid antigen binding. An important paralog of this gene is CD1A.

CD1b Molecule

Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.

Adaptive immune response Source: UniProtKB-KW
Antigen processing and presentation, endogenous lipid antigen via MHC class Ib Source: GO_Central
Antigen processing and presentation, exogenous lipid antigen via MHC class Ib Source: GO_Central
Positive regulation of T cell mediated cytotoxicity Source: GO_Central
Regulation of immune response Source: Reactome

Lysosome membrane; Endosome membrane; Cell membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.

Extracellular: 18-303
Helical: 304-324
Cytoplasmic: 325-333