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QPRT Matched Antibody Pair (952) (APMAB-952LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-QPRT polyclonal antibody, 100 ug
Detection Antibody
Anti-QPRT Mouse monoclonal, IgG1 antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Alternative Names
Quinolinate Phosphoribosyltransferase; Nicotinate-Nucleotide Pyrophosphorylase (Carboxylating); EC 2.4.2.19; QPRTase; Nicotinate-Nucleotide Pyrophosphorylase [Carboxylating]; Quinolinate Phosphoribosyltransferase [Decarboxylating]; Epididymis Secretory Sperm Binding Protein Li 90n; HEL-S-90n; QAPRTase;
Entrez Gene ID
23475
UniProt ID
Q15274
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For research use only. Not intended for any clinical use.

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