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HOXA1 Matched Antibody Pair (564) (APMAB-564LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-HOXA1 polyclonal antibody, 100 ug
Detection Antibody
Anti-HOXA1 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. The encoded protein may be involved in the placement of hindbrain segments in the proper location along the anterior-posterior axis during development. Two transcript variants encoding two different isoforms have been found for this gene, with only one of the isoforms containing the homeodomain region. [provided by RefSeq, Jul 2008]
Alternative Names
Homeobox A1; Homeobox Protein Hox-1F; Homeo Box A1; HOX1F; HOX A1 Homeodomain Protein; Homeobox Protein Hox-A1;
Entrez Gene ID
3198
UniProt ID
P49639
More Infomation

Belpaire, M., Taminiau, A., Geerts, D., & Rezsohazy, R. (2022). HOXA1, a breast cancer oncogene. Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, 1877(4), 188747.

Zhong, W., Bao, L., Yuan, Y., & Meng, Y. (2021). CircRASSF2 acts as a prognostic factor and promotes breast cancer progression by modulating miR-1205/HOXA1 axis. Bioengineered, 12(1), 3014-3028.

Li, M., Yu, D., Li, Z., Zhao, C., Su, C., & Ning, J. (2021). Long non‑coding RNA AFAP1‑AS1 facilitates the growth and invasiveness of oral squamous cell carcinoma by regulating the miR‑145/HOXA1 axis Retraction in/10.3892/or. 2022.8306. Oncology Reports, 45(3), 1094-1104.

Lyv, X., Wu, F., Zhang, H., Lu, J., Wang, L., & Ma, Y. (2020). Long noncoding RNA ZFPM2-AS1 knockdown restrains the development of retinoblastoma by modulating the MicroRNA-515/HOXA1/Wnt/β-Catenin axis. Investigative ophthalmology & visual science, 61(6), 41-41.

Kim, C. Y., Oh, J. H., Lee, J. Y., & Kim, M. H. (2020). The LncRNA HOTAIRM1 promotes tamoxifen resistance by mediating HOXA1 expression in ER+ breast cancer cells. Journal of Cancer, 11(12), 3416.

Mao, Y., Zhang, L., & Li, Y. (2019). circEIF4G2 modulates the malignant features of cervical cancer via the miR‑218/HOXA1 pathway. Molecular Medicine Reports, 19(5), 3714-3722.

Li, Q., Dong, C., Cui, J., Wang, Y., & Hong, X. (2018). Over-expressed lncRNA HOTAIRM1 promotes tumor growth and invasion through up-regulating HOXA1 and sequestering G9a/EZH2/Dnmts away from the HOXA1 gene in glioblastoma multiforme. Journal of Experimental & Clinical Cancer Research, 37(1), 1-15.

Tian, X., Ma, J., Wang, T., Tian, J., Zhang, Y., Mao, L., ... & Wang, S. (2018). Long non-coding RNA HOXA transcript antisense RNA myeloid-specific 1–HOXA1 axis downregulates the immunosuppressive activity of myeloid-derived suppressor cells in lung cancer. Frontiers in immunology, 9, 473.

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For research use only. Not intended for any clinical use.

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