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CENPJ Matched Antibody Pair (256) (APMAB-256LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-CENPJ monoclonal antibody, 100 ug
Detection Antibody
Anti-CENPJ Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and cognitive disability. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
Alternative Names
Centromere Protein J; Centrosomal P4.1-Associated Protein; LYST-Interacting Protein 1; LAG-3-Associated Protein; CENP-J; CPAP; LIP1; LAP; Microcephaly, Primary Autosomal Recessive 6;
Entrez Gene ID
55835
UniProt ID
Q9HC77
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For research use only. Not intended for any clinical use.

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