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BIRC5 Matched Antibody Pair (139) (APMAB-139LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-BIRC5 polyclonal antibody, 100 ug
Detection Antibody
Anti-BIRC5 Mouse polyclonal antibody, 20 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Alternative Names
Baculoviral IAP Repeat Containing 5; Apoptosis Inhibitor 4; Apoptosis Inhibitor Survivin; Survivin Variant 3 Alpha; API4; Baculoviral IAP Repeat-Containing Protein 5; Baculoviral IAP Repeat-Containing 5; EPR-1; IAP4;
Entrez Gene ID
332
UniProt ID
O15392
More Infomation

He, D., Huang, K., & Liang, Z. (2021). Prognostic value of baculoviral IAP repeat containing 5 expression as a new biomarker in lung adenocarcinoma: a meta-analysis. Expert Review of Molecular Diagnostics, 1-9.

Mamoor, S. (2021). Over-expression of baculoviral IAP repeat containing 5 in human endometrial cancer.

Pahlavan, Y., & Khabbazi, A. (2021). Baculoviral inhibitor of apoptosis family of proteins repeat-containing 5 gene methylation status in peripheral blood mononuclear cells and plasma survivin levels in patients with Behçet’s disease. Archives of Rheumatology, 36(2).

Basha, R., Tran, N., & Ibarra-Aleman, V. (2021). Association of baculoviral inhibitor of apoptosis repeat-containing 5 in the survival of clear cell renal cell carcinoma patients: In silico analysis.

Li, Y., Zhao, Z. G., Luo, Y., Cui, H., Wang, H. Y., Jia, Y. F., & Gao, Y. T. (2020). Dual targeting of Polo-like kinase 1 and baculoviral inhibitor of apoptosis repeat-containing 5 in TP53-mutated hepatocellular carcinoma. World Journal of Gastroenterology, 26(32), 4786.

Zou, J., Liao, X., Zhang, J., & Wang, L. (2019). Dysregulation of miR-195-5p/-218-5p/BIRC5 axis predicts a poor prognosis in patients with gastric cancer. Journal of biological regulators and homeostatic agents, 33(5), 1377-1385.

Sušac, I., Ozretić, P., Gregorić, M., Levačić Cvok, M., Sabol, M., Levanat, S., ... & Musani, V. (2019). Polymorphisms in Survivin (BIRC5 Gene) are associated with age of onset in breast cancer patients. Journal of oncology, 2019.

Zhao, H., Zhang, X., Han, Z., Wang, Z., & Wang, Y. (2018). Plasma anti‐BIRC 5 IgG may be a useful marker for evaluating the prognosis of nonsmall cell lung cancer. FEBS Open Bio, 8(5), 829-835.

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For research use only. Not intended for any clinical use.

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