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Mouse Anti-ZFC3H1 Recombinant Antibody (3A3) (CBMAB-C5641-LY)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
3A3
Antibody Isotype
IgG1, κ
Application
ELISA, IHC-F, WB

Basic Information

Immunogen
Full length recombinant protein corresponding to aa1-359 from human CCDC131 (AAH15679) with GST tag. MW of the GST tag alone is 26kD
Specificity
Human
Antibody Isotype
IgG1, κ
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Target

Full Name
zinc finger, C3H1-type containing
Entrez Gene ID
196441
UniProt ID
O60293
Function
Subunit of the trimeric poly(A) tail exosome targeting (PAXT) complex, a complex that directs a subset of long and polyadenylated poly(A) RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters.
Biological Process
Biological Process RNA processing Source:InterPro
Cellular Location
Nucleus
Excluded from the nucleolus.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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