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Mouse Anti-ZAN Recombinant Antibody (2B6) (CBMAB-Z0020-WJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
2B6
Antibody Isotype
IgG1, κ
Application
ELISA, WB

Basic Information

Immunogen
ZAN (AA19-113) partial recombinant protein with GST tag. Immunogen sequence: KEKPPDQKLV VRSSRDNYVL TQCDFEDDAK PLCDWSQVSA DDEDWVRASG PSPTGSTGAP GGYPNGEGSY LHMESNSFHR GGVARLLSPD LWEQG
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid

Target

Full Name
zonadhesin
Introduction
ZAN (Zonadhesin (Gene/Pseudogene)) is a Protein Coding gene encodes a protein that functions in the species specificity of sperm adhesion to the egg zona pellucida. An allelic polymorphism in this gene results in both functional and frameshifted alleles; the reference genome represents the functional allele. Among its related pathways are Sweet Taste Signaling. An important paralog of this gene is FCGBP.
Entrez Gene ID
7455
UniProt ID
Q9Y493
Alternative Names
Zonadhesin (Gene/Pseudogene); Zonadhesin
Function
Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling.
Biological Process
Biological Process binding of sperm to zona pellucida Source:UniProtKB1 Publication
Biological Process cell-cell adhesion Source:UniProtKB1 Publication
Cellular Location
Cell membrane
Exclusively on the apical region of the sperm head.
Topology
Extracellular: 18-2757
Helical: 2758-2778
Cytoplasmic: 2779-2812
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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