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Mouse Anti-TRAPPC9 Recombinant Antibody (CBYJT-4571) (CBMAB-T4084-YJ)


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Summary

Host Animal
Mouse
Specificity
Human, Mouse
Clone
CBYJT-4571
Antibody Isotype
IgG2b
Application
ELISA, IHC, WB

Basic Information

Specificity
Human, Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TRAPPC9 Gene(Protein Coding) Trafficking Protein Particle Complex 9
Introduction
TRAPPC9 is a protein that likely plays a role in NF-kappa-B signaling. Mutations in TRAPPC9 have been associated with autosomal-recessive cognitive disability.
Entrez Gene ID
Human83696
Mouse76510
UniProt ID
HumanQ96Q05
MouseQ3U0M1
Alternative Names
Trafficking Protein Particle Complex 9; NIK- And IKBKB-Binding Protein; Tularik Gene 1 Protein; TRAPP 120 KDa Subunit; NIBP; Trafficking Protein Particle Complex Subunit 9; NIK And IKK-Beta Binding Protein; IKK2 Binding Protein
Function
Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi.
Biological Process
Biological Process cerebral cortex development Source:GO_Central1 Publication
Biological Process endoplasmic reticulum to Golgi vesicle-mediated transport Source:ComplexPortal1 Publication
Biological Process neuron differentiation Source:Ensembl
Biological Process positive regulation of NF-kappaB transcription factor activity Source:Ensembl
Biological Process vesicle coating Source:ComplexPortal1 Publication
Biological Process vesicle tethering Source:ComplexPortal1 Publication
Cellular Location
Golgi apparatus, cis-Golgi network
Endoplasmic reticulum
Cytoplasm
Processes and cell bodies of neurons.
Involvement in disease
Intellectual developmental disorder, autosomal recessive 13 (MRT13):
A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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