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Mouse Anti-TOB2 Recombinant Antibody (CBYJT-4138) (CBMAB-T3585-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-4138
Antibody Isotype
IgG2b, κ
Application
S-ELISA, ELISA, WB

Basic Information

Immunogen
TOB2 (AAH38957, 1 a.a. ~ 344 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa
Specificity
Human
Antibody Isotype
IgG2b, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.2
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 1-344

Target

Full Name
transducer of ERBB2, 2
Introduction
TOB2 belongs to the TOB family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.
Entrez Gene ID
10766
UniProt ID
Q14106
Alternative Names
Transducer Of ERBB2, 2; Transducer Of ErbB-2 2; Protein Tob4; TROB2; TOB4; Protein Tob2; KIAA1663; APRO5; TOBL
Function
Anti-proliferative protein inhibits cell cycle progression from the G0/G1 to S phases.
Biological Process
Biological Process female gamete generation Source:ProtInc1 Publication
Biological Process negative regulation of cell population proliferation Source:ProtInc1 Publication
Biological Process negative regulation of osteoclast differentiation Source:Ensembl
Biological Process osteoclast differentiation Source:Ensembl
Biological Process positive regulation of ossification Source:Ensembl
Biological Process regulation of gene expression Source:GO_Central1 Publication
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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