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Mouse Anti-TNFAIP8 Recombinant Antibody (CBYJT-3643) (CBMAB-T3000-YJ)

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3643
Antibody Isotype
IgG2b
Application
IHC-P

Basic Information

Immunogen
Recombinant Human TNFAIP8 protein
Specificity
Human
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TNF Alpha Induced Protein 8
Introduction
TNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Among its related pathways are Metabolism and Glycerophospholipid biosynthesis. Gene Ontology (GO) annotations related to TNFAIP8 include cysteine-type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of TNFAIP8 is TNFAIP8L3.
Entrez Gene ID
UniProt ID
Alternative Names
TNF Alpha Induced Protein 8; Head And Neck Tumor And Metastasis-Related Protein; NF-Kappa-B-Inducible DED-Containing Protein; TNF-Induced Protein GG2-1; MDC-3.13; SCC-S2; NDED
Function
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
Biological Process
Biological Process negative regulation of apoptotic processSource:ProtInc1 Publication
Biological Process positive regulation of apoptotic processSource:UniProtKB1 Publication
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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