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Mouse Anti-Tlr12 Recombinant Antibody (CBYJT-3355) (CBMAB-T2649-YJ)


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Summary

Host Animal
Mouse
Specificity
Mouse
Clone
CBYJT-3355
Antibody Isotype
IgM
Application
WB

Basic Information

Immunogen
This antibody was developed against amino acids 791-821 of mouse TLR12; GenBank NP_991392.1
Specificity
Mouse
Antibody Isotype
IgM
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 791-821

Target

Full Name
Toll-Like Receptor 12
Introduction
Tlr12 participates in the innate immune response to microbial agents. Tlr12 acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. It plays a role in preventing infection of internal organs of the urogenital system.
Entrez Gene ID
384059
UniProt ID
Q6QNU9
Alternative Names
Tlr11; Gm1365
Function
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Plays a role in preventing infection of internal organs of the urogenital system.
Biological Process
Biological Process defense response to protozoanSource:MGI1 Publication
Biological Process inflammatory responseSource:GO_Central1 Publication
Biological Process innate immune responseSource:UniProtKB-KW
Biological Process toll-like receptor signaling pathwaySource:GO_Central1 Publication
Cellular Location
Membrane
Topology
Extracellular: 22-709
Helical: 710-730
Cytoplasmic: 731-906
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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