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Rat Anti-Tlr11 Recombinant Antibody (CBYJT-3353) (CBMAB-T2647-YJ)

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Summary

Host Animal
Rat
Specificity
Mouse
Clone
CBYJT-3353
Antibody Isotype
IgG2b
Application
ICFC, CyTOF

Basic Information

Immunogen
E. coli-derived recombinant mouse TLR11, Thr209-Gln325, Accession # Q6R5P0
Specificity
Mouse
Antibody Isotype
IgG2b
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, Trehalose
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 209-325

Target

Full Name
Toll-Like Receptor 11
Introduction
Tlr11 participates in the innate immune response to microbial agents. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Entrez Gene ID
UniProt ID
Alternative Names
Gm287
Function
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Biological Process
Biological Process inflammatory responseSource:GO_Central1 Publication
Biological Process innate immune responseSource:UniProtKB-KW
Biological Process response to bacteriumSource:MGI1 Publication
Biological Process toll-like receptor signaling pathwaySource:GO_Central1 Publication
Cellular Location
Membrane
Topology
Extracellular: 31-721
Helical: 722-742
Cytoplasmic: 743-926
More Infomation
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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