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Mouse Anti-THY1 Recombinant Antibody (CBYJT-3069) (CBMAB-T2327-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-3069
Antibody Isotype
IgG1
Application
ELISA, ICC, IHC-P, WB

Basic Information

Immunogen
Purified recombinant fragment of human THY1 (aa17-132) expressed in E. coli.ImmunogenType: Recombinant protein
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Epitope
aa 17-132

Target

Full Name
THY1 Gene(Protein Coding) Thy-1 Cell Surface Antigen
Introduction
THY1 is a cell surface glycoprotein and member of the immunoglobulin superfamily of proteins. THY1 is involved in cell adhesion and cell communication in numerous cell types, but particularly in cells of the immune and nervous systems. THY1 is widely used as a marker for hematopoietic stem cells. THY1 may play a role as a tumor suppressor in nasopharyngeal carcinoma.
Entrez Gene ID
7070
UniProt ID
P04216
Alternative Names
Thy-1 Cell Surface Antigen; Thy-1 Antigen; CDw90; Thy-1 Membrane Glycoprotein; Thy-1 T-Cell Antigen; CD90 Antigen; CD90;
Function
May play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain.
Biological Process
Biological Process angiogenesisSource:UniProtKB
Biological Process cell-cell adhesionSource:UniProtKB
Biological Process cell-cell signalingSource:UniProtKBBy Similarity
Biological Process cytoskeleton organizationSource:UniProtKB
Biological Process focal adhesion assemblySource:UniProtKB
Biological Process integrin-mediated signaling pathwaySource:UniProtKB1 Publication
Biological Process negative regulation of axonogenesisSource:UniProtKB
Biological Process negative regulation of cell migrationSource:UniProtKB
Biological Process negative regulation of neuron projection regenerationSource:UniProtKBBy Similarity
Biological Process negative regulation of protein kinase activitySource:UniProtKB
Biological Process negative regulation of protein tyrosine kinase activitySource:UniProtKB
Biological Process negative regulation of T cell receptor signaling pathwaySource:UniProtKB
Biological Process positive regulation of cellular extravasationSource:UniProtKB1 Publication
Biological Process positive regulation of focal adhesion assemblySource:UniProtKB1 Publication
Biological Process positive regulation of GTPase activitySource:UniProtKB
Biological Process positive regulation of heterotypic cell-cell adhesionSource:UniProtKB1 Publication
Biological Process positive regulation of release of sequestered calcium ion into cytosolSource:UniProtKB
Biological Process positive regulation of T cell activationSource:UniProtKB
Biological Process protein autophosphorylationSource:Ensembl
Biological Process receptor clusteringSource:UniProtKB
Biological Process regulation of cell-matrix adhesionSource:UniProtKB1 Publication
Biological Process regulation of Rho-dependent protein serine/threonine kinase activitySource:UniProtKBBy Similarity
Biological Process response to axon injurySource:Ensembl
Biological Process retinal cone cell developmentSource:UniProtKB
Biological Process T cell receptor signaling pathwaySource:UniProtKB
Cellular Location
Cell membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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