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Mouse Anti-TCERG1 Recombinant Antibody (CBYJT-2241) (CBMAB-T1350-YJ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJT-2241
Antibody Isotype
IgG1
Application
ELISA, FC, ICC, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% Sodium Azide
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
TCERG1 Gene(Protein Coding)


Transcription Elongation Regulator 1
Introduction
TCERG1 is a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. TCERG1 interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain.
Entrez Gene ID
10915
UniProt ID
O14776
Alternative Names
Transcription Elongation Regulator 1; TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase II, S, 150kD; TATA Box-Binding Protein-Associated Factor 2S; Transcription Factor CA150; Co-Activator Of 150 KDa; TAF2S; CA150; Urn1
Function
Transcription factor that binds RNA polymerase II and inhibits the elongation of transcripts from target promoters. Regulates transcription elongation in a TATA box-dependent manner. Necessary for TAT-dependent activation of the human immunodeficiency virus type 1 (HIV-1) promoter.
Biological Process
Biological Process mRNA processingIDA:ARUK-UCL1 Publication
Biological Process negative regulation of transcription by RNA polymerase IIIDA:BHF-UCL1 Publication
Biological Process negative regulation of transcription elongation by RNA polymerase IITAS:ARUK-UCL1 Publication
Biological Process positive regulation of transcription by RNA polymerase IIIDA:ARUK-UCL1 Publication
Biological Process positive regulation of transcription elongation by RNA polymerase IITAS:ARUK-UCL1 Publication
Biological Process RNA splicingIDA:ARUK-UCL1 Publication
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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