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Mouse Anti-SUGCT Recombinant Antibody (CBXS-4374) (CBMAB-S1617-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4374
Antibody Isotype
IgG2a, κ
Application
ELISA

Basic Information

Immunogen
SUGCT (NP_079004.1, 335 a.a.-434 a.a) partial recombinant protein with GST tag
Specificity
Human
Antibody Isotype
IgG2a, κ
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Succinyl-CoA:Glutarate-CoA Transferase
Introduction
This gene encodes a protein that is similar to members of the CaiB/baiF CoA-transferase protein family. Mutations in this gene are associated with glutaric aciduria type III. Alternate splicing results in multiple transcript variants.
Entrez Gene ID
79783
UniProt ID
Q9HAC7
Alternative Names
C7orf10; DERP13; GA3; ORF19
Function
Catalyzes the succinyl-CoA-dependent conversion of glutarate to glutaryl-CoA. Can use different dicarboxylic acids as CoA acceptors, the preferred ones are glutarate, succinate, adipate, and 3-hydroxymethylglutarate.
Cellular Location
Mitochondrion
Involvement in disease
Glutaric aciduria 3 (GA3):
A metabolic disorder due to peroxisomal glutaryl-CoA oxidase deficiency and characterized by the excretion of abnormal quantities of glutaric acid but low 3-hydroxyglutaric acid.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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