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Mouse Anti-SPOCK2 Recombinant Antibody (CBXS-4691) (CBMAB-S1925-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-4691
Antibody Isotype
IgG1
Application
IP, WB

Basic Information

Immunogen
NS0-derived recombinant human Testican 2/SPOCK2 Glu23-Trp424
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 2
Introduction
This gene encodes a protein which binds with glycosaminoglycans to form part of the extracellular matrix. The protein contains thyroglobulin type-1, follistatin-like, and calcium-binding domains, and has glycosaminoglycan attachment sites in the acidic C-terminal region. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
Entrez Gene ID
9806
UniProt ID
Q92563
Alternative Names
SPARC/Osteonectin, Cwcv And Kazal Like Domains Proteoglycan 2; Sparc/Osteonectin, Cwcv And Kazal-Like Domains Proteoglycan (Testican) 2; SPARC/Osteonectin, CWCV, And Kazal-Like Domains Proteoglycan 2; Testican-2; KIAA0275; TICN2;
Function
May participate in diverse steps of neurogenesis. Binds calcium.
Biological Process
Biological Process cellular response to leukemia inhibitory factorIEA:Ensembl
Biological Process extracellular matrix organization1 PublicationNAS:UniProtKB
Biological Process negative regulation of endopeptidase activityManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Biological Process peptide cross-linking via chondroitin 4-sulfate glycosaminoglycanIEA:Ensembl
Biological Process positive regulation of cell motilityManual Assertion Based On ExperimentTAS:ParkinsonsUK-UCL
Biological Process positive regulation of cell-substrate adhesionIEA:Ensembl
Biological Process regulation of cell differentiation1 PublicationNAS:UniProtKB
Biological Process synapse assembly1 PublicationNAS:UniProtKB
Cellular Location
Secreted, extracellular space, extracellular matrix
PTM
Contains chondroitin sulfate and heparan sulfate O-linked oligosaccharides.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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