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Mouse Anti-SNAPC4 Recombinant Antibody (CBXS-3445) (CBMAB-S6176-CQ)


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Summary

Host Animal
Mouse
Specificity
Human
Clone
CBXS-3445
Application
WB

Basic Information

Immunogen
Partial sequence of recombinant Full length protein to human SNAP190
Specificity
Human
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
SNAPC4
Introduction
This gene encodes the largest subunit of the small nuclear RNA-activating protein (SNAP) complex. The encoded protein contains a Myb DNA-binding domain, and is essential for RNA polymerase II and III polymerase transcription from small nuclear RNA promoters. A mutation in this gene is associated with ankylosing spondylitis.
Entrez Gene ID
6621
UniProt ID
Q5SXM2
Alternative Names
Small Nuclear RNA Activating Complex Polypeptide 4; Proximal Sequence Element-Binding Transcription Factor Subunit Alpha; SnRNA-Activating Protein Complex 190 KDa Subunit; PSE-Binding Factor Subunit Alpha; SNAPc 190 KDa Subunit; PTF Subunit Alpha; SNAPc Subunit 4;
Function
Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.
Biological Process
Biological Process snRNA transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Biological Process snRNA transcription by RNA polymerase IIIManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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